Comparison of remineralization by fluoride varnishes with and without casein phosphopeptide amorphous calcium phosphate in primary teeth
Objective: To compare MI (5% NaF with 2% CPP-ACP) and Prevident (5% NaF) varnishes in remineralizing caries-like lesions in primary teeth regarding calcium and phosphate enamel content and lesion depth. Material and methods: Caries-like lesions were created in 48 primary teeth which were divided into 2 halves; one left untreated (control) and the other half treated with MI or Prevident varnishes. Calcium and phosphate content was assessed using energy dispersive X-ray spectrometer and reduction in lesion depth was assessed using polarized light microscopy. Demineralization and remineralization values in each group were compared using paired t test and percentage change between groups was compared using t test and Mann Whitney U test. Results: A greater percentage increase of calcium was observed in MI than Prevident specimens (median = 8.97 and 2.67, p <.0001), with greater calcium phosphate ratio percentage increase (median = 28.96 and 7.40) and phosphate percentage reduction (median = 15.5 and 4.51). The mean (SD) percentages reduction in lesion depth in the MI varnish was significantly greater than in Prevident varnish (44.41 (7.12) and 22.73 (9.35), p <.0001). Conclusions: MI varnish had better remineralization effect in primary teeth than Prevident varnish in terms of higher mineral content and shallower lesion depth.
Faculty of Dentistry
Health Sciences, General Dentistry
Indexed in Scopus
Indexed in Web Of Science
Amorphous calcium phosphate, deciduous, microscopy, polarization, tooth, tooth remineralization
Salman, Nehal Raid; ElTekeya, Magda; Bakry, Niveen; Omar, Samia Soliman; and El Tantawi, Maha, "Comparison of remineralization by fluoride varnishes with and without casein phosphopeptide amorphous calcium phosphate in primary teeth" (2019). Faculty of Dentistry. 18.