Title

Root maturation and dentin–pulp response to enamel matrix derivative in pulpotomized permanent teeth

Document Type

Article

Abstract

The success of pulpotomy of young permanent teeth depends on the proper selection of dressing materials. This study aimed to evaluate the histological and histomorphometric response of dentin–pulp complex to the enamel matrix derivative (Emdogain® gel) compared to that of calcium hydroxide when used as a pulp dressing in immature young permanent dogs’ teeth. Dentin-like tissues bridging the full width of the coronal pulp at the interface between the injured and healthy pulp tissues were seen after 1 month in both groups. With time, the dentin bridge increased in thickness for calcium hydroxide but disintegrated and fully disappeared for Emdogain-treated group. Progressive inflammation and total pulp degeneration were only evident with Emdogain-treated group. The root apices of Emdogain-treated teeth became matured and closed by cementum that attached to new alveolar bone by a well-oriented periodontal ligament. In young permanent dentition, Emdogain could be a good candidate for periodontium but not dentino–pulpal complex regeneration.

Publication Date

1-17-2014

Faculty

Faculty of Dentistry

Subject Area

Physical Sciences, General Engineering, General Materials Science, Health Sciences, General Medicine

Indexed in Scopus

yes

Indexed in Web Of Science

yes

DOI

https://doi.org/10.1177/2041731414521707

Volume

5

Keywords

calcium hydroxide, dentin bridge and histomorphometric analysis, enamel matrix derivative, Pulpotomy

eISSN

20417314

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